Best Ergonomic Mouse in 2023

Ergonomic mice have grown in popularity as computer users seek a comfortable and efficient experience in their daily tasks. They’re designed to significantly reduce muscle strain and discomfort often associated with using traditional mice, and promote a comfortable, natural position for your hand and wrist. Ergonomic mice can help alleviate the risk of repetitive strain injuries and other musculoskeletal issues associated with extended computer use.

An ergonomic mouse comes in various shapes, sizes, and designs, tailored to fit individual hand postures and grip styles. Some may have a vertical orientation, while others may feature trackballs or additional buttons to maximize accessibility and ease of use. These unique designs not only enhance comfort but can also improve accuracy and efficiency when working on tasks that require precise cursor control.

When purchasing the best ergonomic mouse for your needs, it’s essential to consider factors such as shape, size, button placement, and connectivity options (e.g., wired or wireless). Your choice should properly fit your hand size and grip style, ensuring that your hand and wrist remain in a relaxed, neutral position while in use. This will help prevent strain on muscles and joints, which is vital when using a computer for extended periods.

After conducting thorough research and testing numerous ergonomic mice, we’ve identified the top options that can greatly improve your computing experience by prioritizing comfort, efficiency, and ergonomics.

Best Ergonomic Mice

We present to you our carefully curated list of the best ergonomic mice available. These devices prioritize comfort, efficiency, and functionality, making them the perfect choice for users seeking a more ergonomic mouse.

Logitech Lift Vertical Ergonomic Mouse

Logitech Lift Vertical Ergonomic Mouse

An excellent option for those seeking comfort and improved wrist posture with their ergonomic mouse.


  • Elevated 57-degree angle for wrist comfort
  • Smooth SmartWheel scrolling
  • Versatile connectivity options


  • Slightly heavier than other mice
  • Designed for small to medium hands
  • Additional drivers needed for some OS compatibility

The Logitech Lift Vertical Ergonomic Mouse is a wireless, Bluetooth-connected mouse designed to provide comfortable wrist positioning and alleviate discomfort during extended periods of computer use. Its unique 57-degree angle promotes a more natural and relaxed arm posture, easing strain during long work sessions.

The SmartWheel scrolling feature makes navigating pages and documents a breeze, with smooth and seamless transitions between precision and speed-scrolling. The Lift Vertical Ergonomic Mouse offers four easily accessible customizable buttons that can be programmed for shortcuts specific to each user’s needs.

Connecting to multiple devices is simple with the Lift mouse, making it ideal for those who work across various platforms. Compatibility extends to Windows, macOS, iPadOS, Chrome OS, Linux, and Android, but be aware that additional drivers may be needed for some operating systems outside Windows and macOS.

Battery life should not be a concern, as one AA battery offers up to 24 months of usage. However, potential buyers should note that this mouse is specifically designed for small to medium hands and may not be suitable for users with larger hands.

Overall, the Logitech Lift Vertical Ergonomic Mouse is a wise investment for those seeking to improve their workstation’s comfort and functionality.

Anker 2.4G Wireless Ergonomic Optical Mouse

Anker Ergonomic Mouse

The Anker 2.4G Wireless Ergonomic Optical Mouse is a versatile and comfortable option for reducing strain and improving precision during computer use.


  • Encourages healthy wrist and arm positions
  • 800 / 1200 / 1600 DPI resolution for smooth and precise tracking
  • Convenient next/previous webpage browsing buttons


  • May feel slippery for some users
  • Enters power saving mode after 8 minutes of idle time
  • AAA batteries required (not included)

This Anker ergonomic mouse is designed with a scientific ergonomic layout that promotes a neutral “handshake” position for your wrist and arm. This positioning reduces strain and facilitates smoother movement during extended use. The mouse features an optical tracking technology with 800 / 1200 / 1600 DPI resolution, providing more sensitivity than standard optical mice for accurate tracking on various surfaces.

The added next/previous buttons on the side of the mouse make it an ideal choice for internet surfers, gamers, and those who work long hours at the computer. These buttons provide a convenient way to navigate through webpages and documents effortlessly.

One downside to this mouse is that its surface may feel slippery for some users, making it difficult to grip and lift. Additionally, the mouse enters a power-saving mode after 8 minutes of inactivity, requiring a button press to wake it. While this feature saves battery life, it may be inconvenient for some users. Furthermore, the mouse requires 2 AAA batteries, which are not included in the package.

Overall, the Anker 2.4G Wireless Ergonomic Optical Mouse is a solid option for those seeking a comfortable, efficient mouse that helps prevent strain during extended computer usage.

Logitech MX Vertical Wireless Mouse

Logitech MX Vertical Wireless Mouse

The Logitech MX Vertical Wireless Mouse is an excellent choice for users looking to reduce strain and improve comfort without sacrificing performance.


  • Natural handshake position for reduced muscular activity
  • Unique 57° angle for improved wrist posture
  • Advanced optical tracking with adjustable cursor speed


  • Takes time to get accustomed to the design
  • Unsuitable for small hands
  • Can be challenging for gaming or high-precision tasks

The Logitech MX Vertical Wireless Mouse is specifically designed to offer an ergonomic and comfortable experience for those who spend long hours at the computer. The natural handshake position, along with the 57° vertical angle, has been carefully crafted to minimize wrist pressure, reduce muscle strain, and prevent repetitive stress injuries.

The mouse’s advanced optical tracking technology comes with 4000 DPI high-precision sensor, ensuring a responsive performance while reducing hand movements and overall fatigue. You can easily adjust the cursor speed according to your requirements with the touch of a button, ensuring smooth and efficient workflow. Additionally, the textured rubber surface provides a secure and natural grip, fitting a variety of hand shapes and sizes.

Although it may take some time to get used to this unconventional design, the Logitech MX Vertical Wireless Mouse has proven its worth as an ergonomically-designed device that enhances comfort and productivity for its users. Overall, this versatile and rechargeable ergonomic mouse is a worthy investment for those looking to prioritize comfort and health without compromising efficiency.

Amazon Basics Ergonomic Wireless PC Mouse

Amazon Basics Ergonomic Wireless PC Mouse

The Amazon Basics Ergonomic Wireless PC Mouse offers a comfortable and affordable solution for users seeking precision and customization.


  • Adjustable DPI for personal sensitivity preference
  • Ergonomic shape with rubberized grip
  • Convenient back/forward thumb buttons


  • No Bluetooth connectivity
  • Compatibility limited to Windows 7, 8, and 10
  • Occasional glitchy behavior reported

I recently started using the Amazon Basics Ergonomic Wireless PC Mouse, and it has become a valuable addition to my desktop setup. Its ergonomic shape and rubberized sides make it comfortable to use for extended periods. The customizable DPI settings (600, 1000, 1600, 2400, or 3600 DPI) allow me to fine-tune the mouse sensitivity to match my preferences, resulting in smoother and more precise control in various tasks.

One of the standout features of this mouse is the back/forward thumb buttons, which make navigating web pages a breeze. I’ve found this to be a considerable time-saver, especially during research sessions and casual browsing. Moreover, the advanced optical sensor ensures that the mouse works well on a wide range of surfaces, further adding to its practicality.

While the Amazon Basics mouse is an excellent choice for most users, it does have its limitations. The lack of Bluetooth connectivity might be a drawback for some, but the 2.4 GHz wireless connection proved to be reliable in my experience, with a range of up to 33 feet. Additionally, the mouse is compatible exclusively with Windows 7, 8, and 10, which may deter users with different operating systems from considering this option.

In summary, the Amazon Basics Ergonomic Wireless PC Mouse is an affordable and functional choice for anyone looking for a comfortable and customizable wireless mouse. While it has its limitations, its ergonomic design, adjustable DPI settings, and convenient thumb buttons make it a worthwhile option to consider for Windows users.

Amazon Basics Wireless Computer Mouse

Amazon Basics Wireless Computer Mouse

For those seeking an affordable, reliable, and simple wireless mouse, this Amazon Basics option is worth considering.


  • Budget-friendly
  • Easy installation
  • Smooth and precise performance


  • Finish may wear off with use
  • Not suitable for gaming
  • USB nano receiver can be fragile

The Amazon Basics Wireless Computer Mouse is designed as a straightforward solution for users who need a functional mouse for everyday tasks. With its smooth and precise performance, this wireless optical 3-button mouse works seamlessly with laptops, desktops, and netbook PCs. Its 2.4 GHz wireless technology offers a strong and dependable connection, so you don’t have to worry about dropping signals or frequent lagging.

However, this mouse isn’t ideal for those who require advanced features or precision. Gamers, designers, and other professionals who need exceptional tracking abilities might find this mouse unsuitable for their needs. The USB nano receiver, while convenient due to its compact size, can be delicate and may potentially break if not handled with care.

Despite these downsides, the Amazon Basics Wireless Computer Mouse with USB Nano Receiver – Black is an excellent choice for users who want an easy-to-use and cost-effective solution for their daily computing needs. It’s compatible with a variety of Windows operating systems and has a simple setup process that ensures a hassle-free experience. So if you’re in search of a basic, yet efficient wireless mouse, this Amazon Basics option is worth taking a look at.

Amazon Basics Full Size Ergonomic Wireless PC Mouse

Amazon Basics Full Size Ergonomic Wireless Mouse

This Amazon Basics ergonomic wireless mouse is a reliable option for day-to-day tasks with some minor drawbacks to consider.


  • Comfortable ergonomic design for right-handed users
  • Affordable price point
  • Long battery life


  • Requires a USB receiver, not Bluetooth compatible
  • Not ideal for gaming or heavy use
  • Potentially less comfortable for left-handed users

The Amazon Basics Full Size Ergonomic Wireless PC Mouse offers a comfortable grip with its gently curved profile, specifically designed for right-handed users. This mouse’s 1600 DPI optical sensor provides adequate performance for most day-to-day tasks, making it a suitable choice for office work or casual computer use.

This mouse includes a full-size wireless design and connects via a small USB receiver, which may be less convenient than a Bluetooth connection for some users. While it offers fast scrolling and forward/back thumb buttons, it may not be the best choice for gaming or heavy-duty computing due to its slightly heavyweight and basic feature set.

The 2.4 GHz non-Bluetooth wireless connection may limit portability for some, but the mouse’s decent battery life, along with its on/off switch, helps extend its usability. The Amazon Basics Full Size Ergonomic Wireless Mouse is an affordable option for those seeking a comfortable and functional wireless mouse, but left-handed users and those looking for more advanced features may want to explore other options.

Amazon Basics 3-Button USB Wired Mouse

Amazon Basics 3-Button USB Wired Mouse

A budget-friendly, simple option for those seeking a reliable wired ergonomic mouse with basic functionality.


  • Comfortable ergonomic grip
  • Compatible with Windows and Mac OS
  • Plug and play design for easy use


  • Limited to 3 buttons and 1000 DPI sensitivity
  • Requires adapter for USB Type-C ports
  • Some users report inconsistent button feel

The Amazon Basics 3-Button USB Wired Mouse is a straightforward and affordable choice for those in need of a simple ergonomic mouse. Its full-size design ensures a comfortable grip, allowing for extended use without straining your hand or wrist. This mouse is also compatible with both Windows and Mac operating systems, making it a versatile option regardless of your preferred platform.

While it may not have the bells and whistles of more advanced mice, the 3-button design of the Amazon Basics mouse covers the essential functions: left, right, and middle-wheel click. The scroll wheel also ensures smooth navigation through web pages and documents. With its 1000 DPI sensitivity, users can expect precise control, even if it may be limited compared to more customizable ergonomic mice.

However, those with laptops or computers featuring USB Type-C ports will need to purchase an adapter to use this mouse, as it comes with a standard USB Type-A connection. Additionally, some reviews indicate inconsistent button feel and occasional difficulties with maintaining a click. Despite these drawbacks, the Amazon Basics 3-Button USB Wired Mouse remains a worthwhile choice for those seeking a budget-friendly ergonomic mouse with basic functionality.

Amazon Basics 3-Button Wired USB Computer Mouse

Amazon Basics 3-Button Wired USB Computer Mouse

A reliable and affordable choice for those seeking a simple, functional ergonomic mouse.


  • Easy plug-and-go setup
  • Precise tracking with 1000 dpi optical sensor
  • Compatible with Windows and Mac OS


  • Wired design may limit movement
  • Basic 3-button configuration
  • USB-A connector may require an adapter for USB-C devices

The Amazon Basics 3-Button Wired USB Computer Mouse is a straightforward and efficient solution for computer navigation. It offers responsive cursor control with its high-definition optical tracking, ensuring precise tracking for effortless text selection and fingertip control. Its compatibility with both Windows and Mac OS allows users to enjoy its functionality across different platforms.

Despite being a budget-friendly option, this ergonomic mouse doesn’t compromise on performance. It comes with a USB-A connector, which might require an additional adapter for USB-C devices, but other than that, it’s ready for instant use. The plug-and-go feature eliminates the need for complex setups, making it ideal for users who appreciate simplicity.

A possible downside to this Amazon Basics mouse is its wired design, which may limit movement and potentially clutter your workspace. Additionally, it only has a basic 3-button configuration, lacking any extra buttons for customizable functionality. However, this simplicity might be preferred by those seeking a no-frills device. Overall, the Amazon Basics 3-Button Wired USB Computer Mouse is a reliable and economical option for users in search of an ergonomic mouse that gets the job done.

Amazon Basics 6-Button Ergonomic Wireless Mouse

Amazon Basics 6-Button Ergonomic Wireless Mouse

This Amazon Basics mouse offers a great ergonomic design and functionality at an affordable price.


  • Comfortable ergonomic grip with thumb rest
  • 6-button design for dynamic usage
  • Adjustable sensitivity levels (800, 1200, 1600 DPI)


  • Not suitable for users with large hands
  • May experience occasional cursor movement issues
  • USB receiver may be fragile

The Amazon Basics 6-Button Ergonomic 2.4GHz Wireless Mouse is designed for users seeking both comfort and functionality. The ergonomic grip with a thumb rest and larger design fits comfortably in the palm of your hand, providing a more enjoyable user experience during extended periods of use. The 6-button design, including the left, right, middle, forward, and backward buttons, as well as the DPI switch button, offers dynamic usability for various tasks.

One of the appealing features of this mouse is the adjustable sensitivity levels, allowing users to customize the precision control to their preference. With options of 800, 1200, or 1600 DPI, you can easily switch between different sensitivity settings based on your needs.

However, some users may find this mouse unsuitable for users with larger hands, as its size may be better suited for individuals with small to medium-sized hands. Additionally, there have been reports of unanticipated cursor movement and scrolling issues, which may be a drawback for some users. It’s also worth noting that the USB receiver may be fragile and might break when frequently moved between devices.

Overall, the Amazon Basics 6-Button Ergonomic 2.4GHz Wireless Mouse is a solid choice for those looking for a comfortable and functional mouse at an affordable price, but be aware of the potential downsides mentioned.

Buying Guide

Choosing the best ergonomic mouse can significantly improve your productivity and reduce any discomfort that arises from long hours of using your computer. In this buying guide, we will walk you through key features to consider when looking for the perfect ergonomic mouse.

Adjustable DPI: DPI (dots per inch) measures the sensitivity of a mouse. A higher DPI means that your cursor will move faster across the screen. It is essential to choose a mouse with adjustable DPI settings so that you can find the perfect sensitivity for your needs.

Style of grip: Ergonomic mice come in various styles, such as palm, claw, and fingertip grip. Your personal preference and comfort should guide your decision here, as each style offers different advantages and supports your hand differently.

Wired or wireless: Consider whether you prefer a wired or wireless ergonomic mouse. While wireless options offer greater freedom, they may require battery replacement or recharge more frequently than their wired counterparts.

Programmable buttons/features

Many ergonomic mice have programmable buttons that can be customized to your preference for quick access to frequently used functions. This feature can save you time and improve workflow. Make sure to choose a mouse that offers an appropriate number of programmable buttons for your needs.

Aesthetics and build quality

While not as crucial as functionality and comfort, aesthetics and build quality should also be considered. Choose an ergonomic mouse made from high-quality materials for enhanced durability and a sleek design that complements your workspace.

By considering these features and prioritizing your comfort and functionality, you can confidently choose the best ergonomic mouse for your needs. Remember, as individual preferences and needs vary, it’s essential to find a product tailored to your specific requirements.

Frequently Asked Questions

What is the healthiest ergonomic mouse?

The healthiest ergonomic mouse is one that helps reduce strain and discomfort while using it for prolonged periods. Features to look for include adjustable angles, vertical designs, and customizable buttons. Popular models include the Logitech MX Vertical, Anker Vertical Ergonomic Optical Mouse, and the Evoluent VerticalMouse 4.

Are ergonomic mouses beneficial?

Yes, ergonomic mice are beneficial as they promote a more natural hand position, reducing pressure on the wrist and forearm. This can help mitigate the risk of developing repetitive strain injuries such as carpal tunnel syndrome. However, it’s essential to choose the right ergonomic mouse for your specific needs and preferences.

What is the top ergonomic computer mouse for carpal tunnel?

The top ergonomic mouse for carpal tunnel depends on individual preferences, but some popular models include the Logitech MX Ergo, Microsoft Sculpt Ergonomic Mouse, and the RollerMouse Red by Contour Design. These mice promote a neutral wrist posture and help reduce strain that contributes to carpal tunnel symptoms.

Which mouse should be used for wrist injuries?

For wrist injuries, a mouse with support or cushioning can help alleviate pressure on injured areas. Some options to consider include gel cushioned mice like the Fellowes Gel Crystals Mouse or trackball mice like the Kensington Expert Mouse. Always consult with a medical professional for advice specific to your injury.

Which ergonomic mouse offers the most comfort?

Comfort preferences can vary, but some ergonomic mice known for their comfortable designs include the Logitech MX Master 3, Contour Unimouse, and the 3M Ergonomic Optical Mouse. It’s essential to try different options and select the one that best suits your hand size, shape, and personal comfort requirements.

What is the typical cost of an ergonomic mouse?

The cost of an ergonomic mouse can range from around $20 for basic models to over $100 for advanced, feature-rich options. Factors that influence price include materials, additional functionality, and the level of customization available. It is essential to weigh your needs against your budget when making a selection.